*Applications will be reviewed on a rolling-basis.
A postdoctoral fellowship opportunity is currently available in the Division of Biochemical Toxicology, National Center for Toxicological Research (NCTR) of the U.S. Food and Drug Administration (FDA) Jefferson Laboratories Campus located in Jefferson, Arkansas.
Research efforts will include participation in multi-disciplinary efforts in a nationally recognized training program in support of the FDA’s mission and be trained to conduct fundamental and applied research designed to elucidate mechanisms of toxicity and support risk-assessment for chemicals of interest to the FDA. The selected participant will be trained under George Hammons and his team on the development and use of in vitro approaches in assessing the epigenetic effects in the toxicology of nanoparticles. This research will employ cell culture, epigenetic techniques (DNA methylation, histone modification, microRNAs), nanoparticles characterization, and gene expression using various OMICs technology. Through this fellowship, the selected participant will have the opportunity to learn and apply epigenetic tools to address public health-related issues and gain experience in their use geared towards the advancement of regulatory science. S/he will collaborate with FDA investigators at NCTR and with investigators in other FDA centers such as the Center for Food Safety and Applied Nutrition (CFSAN). During the project, s/he will be actively encouraged to present the research at internal and external meetings and publish the findings in peer-reviewed journals.
Anticipated Appointment Start Date: May 2021
This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and FDA. The initial appointment is for one year, but may be renewed upon recommendation of FDA contingent on the availability of funds. The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program. The appointment is full-time at FDA in the Jefferson, Arkansas, area. Participants do not become employees of FDA, DOE or the program administrator, and there are no employment-related benefits.
Completion of a successful background investigation by the Office of Personnel Management is required for an applicant to be on-boarded at FDA. OPM can complete a background investigation only for individuals, including non-US Citizens, who have resided in the US for a total of three of the past five years.
FDA requires ORISE participants to read and sign their FDA Education and Training Agreement within 30 days of his/her start date, setting forth the conditions and expectations for his/her educational appointment at the agency. This agreement covers such topics as the following:
- Non-employee nature of the ORISE appointment;
- Prohibition on ORISE Fellows performing inherently governmental functions;
- Obligation of ORISE Fellows to convey all necessary rights to the FDA regarding intellectual property conceived or first reduced to practice during their fellowship;
- The fact that research materials and laboratory notebooks are the property of the FDA;
- ORISE fellow’s obligation to protect and not to further disclose or use non-public information.
The qualified candidate should have received a doctoral degree in one of the relevant fields, or be currently pursuing the degree with completion by May 31, 2021. Degree must have been received within five years of the appointment start date.
- Basic knowledge of cell biology, cell culture, epigenetic techniques, and nanotechnology use in regulatory research
- Demonstrated written and oral communication skills, able to interpret and analyze research results in publication formats
- Interpersonal skills in collaborative projects and interacting with diverse personnel both internally and externally
- Degree: Doctoral Degree received within the last 60 months or anticipated to be received by 5/31/2021 11:59:00 PM.
- Communications and Graphics Design
- Computer, Information, and Data Sciences
- Life Health and Medical Sciences
- Mathematics and Statistics