The lab focuses on inborn errors of phosphate metabolism and the endocrine regulation of phosphate homeostasis with emphasis on the metabolic and endocrine effects of phosphate.

We are currently pursuing three main lines of research:
1) Clinical research to define markers of disease progression and response to therapy for HHRH, with the long-term goal is to conduct trials for innovative therapies of hypophosphatemic rickets, osteomalacia and myopathy.
2) Basic research using mouse models that develop renal calcifications and hypophosphatemic myopathy, and a Drosophila model to study the role of dietary phosphate on longevity to better understand endocrine and metabolic effects of phosphate.
3) Basic research to understand the role of genes identified in a Drosophila genome-wide RNAi knockdown screen involved in phosphate-signaling using Drosophila and murine models.

Yale University offers exciting opportunities for achievement and growth in New Haven, Connecticut. Conveniently located between Boston and New York, New Haven is the creative capital of Connecticut with cultural resources that include three major museums, a critically-acclaimed repertory theater, state-of-the-art concert hall, and world-renowned schools of Architecture, Art, Drama, and Music.